Despite its name, the Ultimate Recomposition Stack combines the endurance and fat-burning benefits of GW-501516 with the therapeutic, mild anabolic of MK-2866, but adds YK-11 to the mix.
The Ultimate Recomposition SARMs Stack blends endurance-driven fat loss with selective anabolism and myostatin inhibition to push body composition beyond typical recomp limits.
The Ultimate Recomposition SARMs Stack includes:
- NEO SARMs Cardarine (GW-501516) — 10 mg / 50 tablets ×1
- NEO SARMs Ostarine (MK-2866) — 10 mg / 50 tablets ×1
- NEO SARMs YK-11 — 10 mg / 50 tablets ×1
- Novo-Pharm Nolvadex (Tamoxifen Citrate) — 20 mg / 30 tablets ×1
This is not a beginner stack. The inclusion of YK-11 significantly raises both effectiveness and side-effect burden, making liver support, bloodwork, and PCT mandatory.
What’s in the Stack
Endurance & Metabolic Base (GW-501516 – Cardarine)
A PPARδ agonist that boosts aerobic capacity, fat oxidation, and improves lipid profiles.
Healing & Anabolic Support (MK-2866 – Ostarine)
A mild SARM is included to support joint/tendon health, provide a baseline of muscle protein synthesis, and potentially counteract some of the joint dryness associated with YK-11. It is the primary beginner-friendly compound here.
Potent Growth & Myostatin Inhibition (YK-11)
A farnesoid that acts as a partial AR agonist and a myostatin inhibitor. It is highly suppressive, though it can cause dramatic changes in muscle density and strength.
Protocol
| Week | GW-501516 (Cardarine) | MK-2866 (Ostarine) | YK-11 | Support & Notes |
|---|---|---|---|---|
| 1 | 10 mg/day | 15 mg/day | 5 mg/day (split dose) | MANDATORY Baseline Bloodwork. Start strong liver support (TUDCA + NAC). |
| 2 | 15 mg/day | 20 mg/day | 5 mg/day (split) | Endurance improves. Monitor for joint stiffness (YK-11). |
| 3 | 20 mg/day | 20 mg/day | 10 mg/day (split) | Suppression begins. Consider introducing a SERM (e.g., Enclomiphene 6.25mg) on-cycle. |
| 4 | 20 mg/day | 20 mg/day | 10 mg/day (split) | Aggressive leaning/hardening effect. Fatigue from suppression is likely. |
| 5 | 20 mg/day | 20 mg/day | 10 mg/day (split) | Mid-Cycle Bloodwork is CRITICAL to check liver enzymes (ALT/AST) and lipids. |
| 6 | 20 mg/day | 20 mg/day | 10 mg/day (split) | Endurance is high, but systemic stress is also high. |
| 7 | 20 mg/day | 20 mg/day | 10 mg/day (split) | Final week of YK-11 & MK-2866. |
| 8 | 20 mg/day | OFF | OFF | GW-only week to aid recovery as suppressive compounds clear. |
| PCT Start | — | — | — | Begin PCT Week 9 (See FAQ) |
Recommendations
Aggressive Liver Support
You must run TUDCA (500mg/day) and NAC (1200mg/day) from start through the end of PCT. YK-11 is highly hepatotoxic.
On-Cycle Therapy (OCT) is Advised
Given the suppression from YK-11 and MK-2866, using a SERM like Enclomiphene Citrate (6.25 to 12.5mg/day) from weeks 3-7 can help maintain endogenous testosterone production and improve how you feel.
Bloodwork is Non-Negotiable
Pre, mid (week 5), and post (5-6 weeks after PCT) panels must include:
- Full Liver Panel (ALT, AST, GGT);
- Lipid Profile;
- Full Hormone Panel (Total/Free Test, LH, FSH, Estradiol).
Diet & Training
To support YK-11, a caloric surplus or maintenance is needed for growth. To leverage GW, high-volume cardio is beneficial. This requires balance.
PCT Preparation
Have a full PCT (e.g., Nolvadex) and all support supplements ready before starting Day 1.
SARMs Recomposition Stack Cheat Sheet

Anonymous –
So far so good. Week 2. Appetite is down from the GW but muscle fullness is up from the YK. Weirdest feeling ever but I like it.
Wes –
worth the wait
C. Davidson –
Finished week 4 and I look like a different person. Entirely. Like it’s literally life changing. Pause now and I’m back on!!
Adam –
YK-11 pumps are actually painful in a good way but Ostarine keeps the joints feeling good. Thanks for free PCT, I actually used less than half the pack of Nolva.