This fat burning SARMs stack is designed as a potential first-cycle introduction for individuals looking to enhance fat loss, improve body composition, and gain performance benefits with a relatively straightforward and moderately suppressive protocol.
It combines the non-hormonal, endurance-boosting effects of GW-501516 (Cardarine) with the mild androgenic, hardening effects of S4 (Andarine).
The goal is to create a noticeable recomp effect — losing fat while preserving or slightly improving muscle hardness and strength — with a lower side-effect burden than more aggressive stacks. A traditional SERM-based PCT is often not required due to S4’s milder suppression profile.
What’s Included
The Beginner’s Fat Burning SARMs Stack combines a powerful non-hormonal endurance compound with a mild, hardening SARM to deliver noticeable recomp results while keeping side effects manageable.
This stack focuses on fat oxidation, performance, and muscle preservation, making it suitable for users new to SARMs who want results without heavy hormonal disruption.
The Beginner’s Fat Burning SARMs Stack includes:
- NEO SARMs Cardarine (GW-501516) — 10 mg / 50 tablets ×1
- NEO SARMs Andarine (S4) — 10 mg / 50 tablets ×1
What’s in the Stack
Endurance & Fat Oxidizer (GW-501516 – Cardarine)
NOT a SARM. It is a PPARδ agonist that dramatically increases aerobic endurance, shifts the body’s fuel preference to burn more fat, and can improve cholesterol profiles. It is associated with rapid cancer development in rodent studies at all doses tested, a risk that is not fully understood in humans.
Hardening & Strength Agent (S4 – Andarine)
A SARM that provides a noticeable “dry” and hard look to muscles, enhances vascularity, and helps maintain strength in a caloric deficit. It is considered one of the milder SARMs in terms of mass gain but is notable for causing vision-related side effects (yellow tint, night vision impairment) that are usually dose-dependent and reversible.
Fat Burning SARMs Stack Protocol
| Week | GW-501516 (Cardarine) | S4 (Andarine) | Support & Notes |
|---|---|---|---|
| 1 | 10 mg/day | 25 mg/day (single dose) | Baseline: Consider basic bloodwork (lipids, liver). Start liver support (NAC). Begin a moderate caloric deficit. |
| 2 | 10 mg/day | 50 mg/day (split 25mg AM/PM) | Endurance during cardio improves. Assess tolerance to S4. |
| 3 | 15 mg/day | 50 mg/day (split) | Fat loss should become more visible. Monitor for vision sides from S4. |
| 4 | 15 mg/day | 50 mg/day (split) | Performance in the gym is enhanced. Lethargy from the deficit is counteracted. |
| 5 | 20 mg/day | 50 mg/day (split) | Common plateau week in cuts; the stack helps push through. |
| 6 | 20 mg/day | 50 mg/day (split) | Strength should be well-maintained. Vascularity increases. |
| 7 | 20 mg/day | 50 mg/day (split) | Final week of S4 dosing. Continue GW. |
| 8 | 20 mg/day | OFF | GW-only week. Continue fat loss and endurance benefits as S4 clears. |
| Post-Cycle | OFF | OFF | Observation. Use natural test support (e.g., Ashwagandha) for 2-3 weeks. |
Stack Recommendations
Start with Diet and Training
This stack is an enhancement, not a replacement. Have a solid diet plan (~300-500 calorie deficit) and consistent training regimen (both resistance and cardio) in place before starting.
Bloodwork is Still Wise
Even for a first cycle, pre and post-cycle blood tests (Testosterone, Free Test, LH, FSH, Lipids, Liver Enzymes) are the only way to know how your body responds and to confirm recovery.
Manage S4 Vision Sides
The 50mg/day dose is chosen to minimize the likelihood of severe vision issues. If a yellow tint or night vision problems occur, they are usually temporary. Taking a 2-day break from S4 often resolves them.
Leverage the Endurance
The most noticeable effect will be from GW. Use it to increase your cardio volume and intensity. You’ll be able to do more, which directly translates to a greater calorie burn.
Have Support on Hand
While not mandatory for PCT, have a natural testosterone booster (like Ashwagandha or Tongkat Ali) ready for post-cycle. Have liver support (NAC) and monitor your blood pressure.
Acknowledge the GW Risk
You must independently research and understand the potential cancer risk associated with GW-501516 before deciding to use it.
Beginner’s Fat Burning SARMs Stack Cheat Sheet

Anonymous –
This is my first time using SARMs and I’m happy so far
Tim –
shipping took a whole week
G. Miller –
Great beginner stack. Highly recommend..