The Ultimate SARMS FAQ by NEO Sarms

We often receive question. However, while some of them definitely require expertise to answer, most have been thoroughly answered by experts before us. Here is a collection of all the most common questions about SARMs (including the ones in our pipeline), and all the answers: thoroughly revised and approved by our team’s most knowledgeable staff.

Can SARMs be stacked with peptides?

Peptides and SARMs combination is one of the safest stacks of different-class compounds. Peptides are responsible for protein synthesis, providing needed nutrients for muscle development, whereas SARMs target androgen receptors in muscle tissue to enhance muscle growth, endurance and strength.

These classes can be stacked and benefit each other. However, the same results can be achieved through adhering to a proper diet and choosing an optimal SARMs stack.

Can SARMs be stacked with prohormones?

SARMs can be stacked with prohormones by advanced users only, as this combination should be approached with caution. Prohormones aren’t targeting muscle tissue specifically, so the HPTA suppression will be severe.

It’s important to note that prohormones are metabolized through the liver, and they can cause its damage. You can combine SARMs and achieve similar effects without experiencing serious side effects.

Can SARMs be stacked with Anavar?

Even though Anavar doesn’t convert into estrogen, which reduces the risks of gynecomastia, it’s still not recommended stacking with SARMs. The combination of Anavar with SARMs should be used only by experienced bodybuilders, it’s not suitable for beginner cycles.

To read more about all the right ways to cchoose the right SARMS for your next cycle, you can check out this post on best SARMS for any fitness goals.

SARMs specifically target muscle and bone tissues, providing similar effects to steroids, You can increase muscle mass, strength gains and endurance with a SARMs stack, without Anavar.

If you have decided to stack Anavar with SARMs, the best options are MK-2866, LGD-4033 and S4. Start with the minimal dosages and closely monitor your reaction to the stack, as Anavar can cause virilization, hair loss and liver damage.

Are SARMs effective in building muscles?

Selective androgen receptor modulators, or SARMs, primarily used for gaining muscle mass, retaining muscle on cutting cycles, and building lean muscle. SARMs bind to the androgen receptors, boosting testosterone production, therefore stimulating muscle growth.

To put it simply, yes, SARMs are designed to keep and promote muscle gains without any androgenic side effects. The most potent SARMs for bulking cycles are RAD-140, MK-677 and LGD-3033.

By the way, here’s a more in-depth post on MK-677 if you want to try this SARM next.

However, SARMs aren’t magic pills, so the results will depend on the intensity of your training and proper diet.

Are SARMs effective in burning fat?

Some SARMs can be beneficial for losing weight, as they promote cell oxidative functions and replace the energy source from glucose to fat. Most of the SARMs can be used on a cutting cycle as well to retain muscle mass and increase strength.

SARMs that are recognized for their fat-burning effects are GW501516, GW-0742, S4, MK-2866 and SR9009.

The calorie deficit and cardio training are still needed to achieve a desirable muscle-to-fat ratio. SARMs won’t provide the same results without exercising or a low-calorie diet.

Do SARMs break fasting?

Since SARMs are PEDs and not nutrient additives, the amount of calories in the pill is minimal. SARMs cycle won’t affect your fasting.

However, for increasing or retaining muscle mass, the body does need protein, carbs and fats. We recommend using intermittent fasting or adhering to a calorie deficit diet for better results.

Should you take SARMs on rest days?

Yes, you have to take SARMs on rest days to keep up the optimal concentration of the compound in the system. Most SARMs have to be administered orally a few times a day, every day during the cycle.

However, there is an exception ― S4. To prevent negative side effects on vision, it’s advised to make small pauses during the cycle. The break can be on a rest day or workout day; it won’t make a difference.

When do SARMs “kick in”?

SARMs start affecting the androgenic receptors as soon as they’re going through the system. However, noticeable effects can be seen later, as the compound needs time to accumulate.

The effects of some SARMs can be seen after two or three weeks. In general, by the 4th week, most SARMs do “kick in,” and the bodybuilder can evaluate first results.

The timing will differ due to SARMs unique features, dosage, cycle length and the compound’s purity. To ensure the safety and effectiveness of the product, purchase compounds only through verified NEOSarms Partners.

Can I take SARMs if I’m sick?

There’s no evidence supporting SARMs effects on the immune system. If you’re sick, there’s a great chance you’ll stop training for a while. In this scenario, SARMs can be beneficial for retaining muscle mass and recovering.

However, if you experience any side effects that may worsen your condition, we recommend taking a pause and continuing the cycle after recovery. 

Can I take SARMs if I’m overweight?

You can take SARMs if you’re overweight, but they won’t be as effective. If you’re maintaining a low-calorie diet and adhere to the exercising schedule, you can try to go on a cutting cycle.

The end results can depend on the fat percentage; the optimal range varies between 10-15%. To strive for better, we advise you to lose weight and revisit the idea of going on a cycle later.

When should you start taking SARMs?

If you have been training for a while and have reached muscle mass plateaus or strength ones, it is a good idea to go on a SARM cycle. SARMs provide muscle and strength gains, enhance endurance and promote fat loss.

Basically, if you have no health contraindications for SARMs cycle, you can implement them into your daily regimen, achieve your goals and set better personal records.

Do SARMs expire?

SARMs, as all bioactive compounds, have an expiration date. For NEOSarms compounds, the shelf life is 24 months, as they come in the form of oral tablets.

If the compound has expired, it might not be as effective. We recommend monitoring expiration dates and using the product before its shelf life ends.

Do SARMs results last?

The results you have achieved during SARMs cycle will last if you continue working out and adhering to a calorie maintenance diet. Maximum muscle gain loss in anecdotal reports is around 5-10% once the cycle is finished.

An Imbalanced lifestyle and lack of training can influence your weight and muscle-to-fat ratio, as it is with every other compound.

To be sure of the safety, purity and efficiency of the product, we recommend purchasing compounds through NEOSarms Partners.

How long should you go off SARMs between cycles?

On average, the bodybuilder has to take 4 weeks off between cycles, where 3 weeks are needed for post-cycle therapy and one week for rest. If you’re a beginner SARMs user, you may want to go on the second cycle to achieve the best results possible, but it isn’t safe.

After SARMs cycle, the body needs some time to restore the hormonal balance and natural testosterone production. The only way to know for sure if you can go on the next cycle is to do the blood work and evaluate:

• Testosterone level;
• AST and ALT levels;
• HDL and LDL levels.

Once your body has recovered, health marks are in order, and the testosterone level aligns with the pre-cycle one, you can safely start the next SAMs cycle.

To prevent liver damage and other negative side effects, it’s important to purchase pure compounds through NEOSarms Partners.

Summary

We sincerely hope this guide helps our clients make the right choice and learn more about SARMS. There’s a lot to this subject, and we’re happy to see the industry growing.

It’s a big part of our mission to provide as much expert and verified information as it is possible, and this article — is our practical way to do it. Also, you can check the SARMS FAQ to get more answers, regarding practical aspects of SARMS cycling in Canada in 2025.